Calendula for burns from radiation therapy
I just love this flower.... I was doing a bit of research because I'm in contact with people every day as a nurse that are being harmed by modern treatments. I ran across this and copied it for the nurse in charge of the oncology, infusion and radiation oncology department. Thought I would pass it on... My uncle was diagnosed in September with stage 3 lung cancer, inoperable at this point so of course, they recommended radiation therapy to shrink the tumor... I have had many discussions with them even prior to this event but they are very indoctrinated. Even though I know they may not think it can help I'm going to make a salve and send it to Jersey in preparation for possible radiation damage to his skin. Maybe I can win them over one little flower at a time.
OPTIONS & TOOLS
No companion articles
DOI: 10.1200/JCO.2004.07.063 Journal of Clinical Oncology - published online before print September 21, 2016
Phase III Randomized Trial of Calendula Officinalis Compared With Trolamine for the Prevention of Acute Dermatitis During Irradiation for Breast Cancer
Top of page
PATIENTS AND METHODS
Authors' Disclosures of P...
The effectiveness of nonsteroid topical agents for the prevention of acute dermatitis during adjuvant radiotherapy for breast carcinoma has not been demonstrated. The goal of this study was to compare the effectiveness of calendula (Pommade au Calendula par Digestion; Boiron Ltd, Levallois-Perret, France) with that of trolamine (Biafine; Genmedix Ltd, France), which is considered in many institutions to be the reference topical agent.
Patients and Methods
Between July 1999 and June 2001, 254 patients who had been operated on for breast cancer and who were to receive postoperative radiation therapy were randomly allocated to application of either trolamine (128 patients) or calendula (126 patients) on the irradiated fields after each session. The primary end point was the occurrence of acute dermatitis of grade 2 or higher. Prognostic factors, including treatment modalities and patient characteristics, were also investigated. Secondary end points were the occurrence of pain, the quantity of topical agent used, and patient satisfaction.
The occurrence of acute dermatitis of grade 2 or higher was significantly lower (41% v 63%; P < .001) with the use of calendula than with trolamine. Moreover, patients receiving calendula had less frequent interruption of radiotherapy and significantly reduced radiation-induced pain. Calendula was considered to be more difficult to apply, but self-assessed satisfaction was greater. Body mass index and adjuvant chemotherapy before radiotherapy after lumpectomy were significant prognostic factors for acute dermatitis.
Calendula is highly effective for the prevention of acute dermatitis of grade 2 or higher and should be proposed for patients undergoing postoperative irradiation for breast cancer.